MolNFT v1 · #109912 · protein
Structure of RNA helicase frh a critical component of the neurospora crassa circadian clock
4XGT · Frq-interacting RNA helicase: “Structure of RNA helicase frh a critical component of the neurospora crassa circadian clock”. X-ray diffraction, 11 pockets (best druggability 0.82). MolNFT v1 #109912 on GenesisL1: 3D structure…
- PDB
- 4XGT
- Type
- protein
- Length
- 961 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Frq-interacting RNA helicase
- UniProt
- Q873J5
- Pockets
- 11 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Frq-interacting RNA helicase | protein | 961 | 44% helix, 14% strand | Q873J5 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 701 | 0.82 | 0.86 | 77 | empty |
| 2 | 244 | 0.72 | 0.87 | 41 | empty |
| 3 | 255 | 0.57 | 0.78 | 26 | empty |
| 4 | 121 | 0.57 | 0.84 | 22 | empty |
| 5 | 120 | 0.39 | 0.75 | 24 | empty |
Compared structures
- 4XGT · Structure of RNA Helicase FRH a Critical Component of the Neurospora Crassa Circadian… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q873J5
- Elsewhere: RCSB PDB 4XGT · PDBe 4XGT · UniProt Q873J5
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