MolNFT v1 · #109769 · protein
N-terminal domain of HSP90 from dictyostelium discoideum in complex with ADP
4XCJ · Heat shock cognate 90 kda protein: “N-terminal domain of HSP90 from dictyostelium discoideum in complex with ADP”. X-ray diffraction, 2 ligands (ADP, MG), 1 pocket (best druggability 0.65). MolNFT v1 #109769 on GenesisL1: 3D…
- PDB
- 4XCJ
- Type
- protein
- Length
- 215 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock cognate 90 kda protein
- UniProt
- P54651
- Ligands
- ADP, MG
- Pockets
- 1 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock cognate 90 kda protein | protein | 215 | 42% helix, 23% strand | P54651 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 238 | 0.65 | 0.83 | 28 | ADP, MG |
Compared structures
- 4XCJ · N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with ADP · the same entry in another collection · chain A against A, TM-score 1.00
- P54651 · AlphaFold monomer V2.0 prediction for heat shock cognate 90 kda protein (P54651) · a predicted model of the same protein · chain A against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54651
- Elsewhere: RCSB PDB 4XCJ · PDBe 4XCJ · UniProt P54651
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