MolNFT v1 · #109768 · protein
Crystal structure of a hexadecameric TF55 complex from S. solfataricus, crystal form II
4XCI · Thermosome subunit beta: “Crystal structure of a hexadecameric TF55 complex from S. solfataricus, crystal form II”. X-ray diffraction, 10 pockets (best druggability 0.82). MolNFT v1 #109768 on GenesisL1: 3D structure, binding sites…
- PDB
- 4XCI
- Type
- protein
- Length
- 762 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thermosome subunit beta; Thermosome subunit alpha
- UniProt
- Q9V2T8, Q9V2S9
- Pockets
- 10 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Thermosome subunit beta | protein | 449 | 51% helix, 16% strand | Q9V2T8 |
| A | Thermosome subunit alpha | protein | 313 | 61% helix, 9% strand | Q9V2S9 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 797 | 0.82 | 0.85 | 76 | empty |
| 2 | 541 | 0.80 | 0.86 | 45 | empty |
| 3 | 196 | 0.69 | 0.86 | 35 | empty |
| 4 | 202 | 0.51 | 0.77 | 24 | empty |
| 5 | 112 | 0.51 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- B–A · 1198 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 4XCI · Crystal structure of a hexadecameric TF55 complex from S. solfataricus, crystal form II · the same entry in another collection · chain B against B, TM-score 1.00
- Q9V2S9 · AlphaFold monomer V2.0 prediction for thermosome subunit alpha (Q9V2S9) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q9V2T8 · AlphaFold monomer V2.0 prediction for thermosome subunit beta (Q9V2T8) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9V2T8
- Every structure of UniProt Q9V2S9
- Elsewhere: RCSB PDB 4XCI · PDBe 4XCI · UniProt Q9V2T8 · UniProt Q9V2S9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.