MolNFT v1 · #109424 · protein
Clostridium difficile fic PROTEIN_0569 mutant S31A, E35A
4X2C · Fic family protein putative filamentation induced by camp…: “Clostridium difficile fic PROTEIN_0569 mutant S31A, E35A”. X-ray diffraction, 1 ligand (PO4), 5 pockets (best druggability 0.46). MolNFT v1 #109424 on GenesisL1: 3D…
- PDB
- 4X2C
- Type
- protein
- Length
- 410 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fic family protein putative filamentation induced by camp protein
- UniProt
- C9YJ22
- Ligands
- PO4
- Pockets
- 5 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 65% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fic family protein putative filamentation induced by camp protein | protein | 207 | 64% helix, 4% strand | C9YJ22 |
| B | Fic family protein putative filamentation induced by camp protein | protein | 203 | 66% helix, 4% strand | C9YJ22 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
- GOL · Glycerol · additive · 5 copies · chains A, B
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.46 | 0.79 | 27 | empty |
| 2 | 127 | 0.43 | 0.76 | 23 | empty |
| 3 | 100 | 0.39 | 0.76 | 21 | GOL |
| 4 | 66 | 0.32 | 0.75 | 12 | empty |
| 5 | 63 | 0.27 | 0.72 | 16 | PO4 |
Interfaces
1 interface between chains.
- A–B · 666 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 4X2C · Clostridium difficile Fic protein_0569 mutant S31A, E35A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C9YJ22
- Elsewhere: RCSB PDB 4X2C · PDBe 4X2C · UniProt C9YJ22
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.