MolNFT v1 · #109408 · protein

Crystal structure of the 2ND SH3 domain from human CD2AP (cms) in complex with a proline-rich peptide (aa 76-91) from human ARAP1

4X1V · CD2-associated protein: “Crystal structure of the 2ND SH3 domain from human CD2AP (cms) in complex with a proline-rich peptide (aa…”. X-ray diffraction. MolNFT v1 #109408 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4X1V
Type: protein
Length: 73 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CD2-associated protein; Arf-gap with rho-gap domain, ank repeat and pH domain- containing…
UniProt: Q9Y5K6, Q96P48

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CD2-associated protein	protein	59	5% helix, 53% strand	Q9Y5K6
B	Arf-gap with rho-gap domain, ank repeat and pH domain- containing protein 1	protein	14	0% helix, 0% strand	Q96P48

Interfaces

1 interface between chains.

A–B · 615 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

4X1V · Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a… · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y5K6 · AlphaFold monomer V2.0 prediction for CD2-associated protein (Q9Y5K6) · a predicted model of the same protein · chain A against A, TM-score 0.88
Q96P48 · AlphaFold monomer V2.0 prediction for arf-gap with rho-gap domain, ank repeat and pH… · a predicted model of the same protein · chain B against A, TM-score 0.33

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y5K6
Every structure of UniProt Q96P48
Elsewhere: RCSB PDB 4X1V · PDBe 4X1V · UniProt Q9Y5K6 · UniProt Q96P48

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