MolNFT v1 · #109284 · protein
Crystal structure of autophagic snare complex
4WY4 · Vesicle-associated membrane protein 8: “Crystal structure of autophagic snare complex”. X-ray diffraction. MolNFT v1 #109284 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4WY4
- Type
- protein
- Length
- 265 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vesicle-associated membrane protein 8; Syntaxin-17; Synaptosomal-associated protein 29
- UniProt
- Q9BV40, P56962, O95721
Structure
x-ray diffraction · 4 distinct chains · 94% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vesicle-associated membrane protein 8 | protein | 64 | 95% helix, 0% strand | Q9BV40 |
| B | Syntaxin-17 | protein | 58 | 91% helix, 0% strand | P56962 |
| C | Synaptosomal-associated protein 29 | protein | 78 | 95% helix, 0% strand | O95721 |
| D | Synaptosomal-associated protein 29 | protein | 65 | 94% helix, 0% strand | O95721 |
Interfaces
6 interfaces between chains.
- A–B · 1657 Ų buried · 11 hydrogen bonds · protein-protein
- C–D · 1566 Ų buried · 16 hydrogen bonds · protein-protein
- B–C · 1358 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 1279 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 407 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4WY4 · Crystal structure of autophagic SNARE complex · the same entry in another collection · chain D against D, TM-score 1.00
- O95721 · AlphaFold monomer V2.0 prediction for synaptosomal-associated protein 29 (O95721) · a predicted model of the same protein · chain D against A, TM-score 0.96
- Q9BV40 · AlphaFold monomer V2.0 prediction for vesicle-associated membrane protein 8 (Q9BV40) · a predicted model of the same protein · chain A against A, TM-score 0.92
- P56962 · AlphaFold monomer V2.0 prediction for syntaxin-17 (P56962) · a predicted model of the same protein · chain B against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BV40
- Every structure of UniProt P56962
- Every structure of UniProt O95721
- Elsewhere: RCSB PDB 4WY4 · PDBe 4WY4 · UniProt Q9BV40 · UniProt P56962 · UniProt O95721
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