MolNFT v1 · #109241 · protein
Aminopeptidase APDKAM598 from the archaeon desulfurococcus kamchatkensis
4WWV · Aminopeptidase from family M42: “Aminopeptidase APDKAM598 from the archaeon desulfurococcus kamchatkensis”. X-ray diffraction, 3 pockets (best druggability 0.67). MolNFT v1 #109241 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4WWV
- Type
- protein
- Length
- 721 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aminopeptidase from family M42
- UniProt
- B8D484
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aminopeptidase from family M42 | protein | 361 | 27% helix, 27% strand | B8D484 |
| B | Aminopeptidase from family M42 | protein | 360 | 29% helix, 27% strand | B8D484 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 665 | 0.67 | 0.75 | 52 | empty |
| 2 | 148 | 0.47 | 0.77 | 31 | empty |
| 3 | 110 | 0.46 | 0.79 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 310 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4WWV · Aminopeptidase APDkam598 from the archaeon Desulfurococcus kamchatkensis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8D484
- Elsewhere: RCSB PDB 4WWV · PDBe 4WWV · UniProt B8D484
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