MolNFT v1 · #10914 · protein
Crystal structure of helicobacter pylori luxs
1J6X · Autoinducer-2 production protein luxs: “Crystal structure of helicobacter pylori luxs”. X-ray diffraction, 2 ligands (MET, ZN), 2 pockets (best druggability 0.72). MolNFT v1 #10914 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1J6X
- Type
- protein
- Length
- 303 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autoinducer-2 production protein luxs
- UniProt
- Q9ZMW8
- Ligands
- MET, ZN
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autoinducer-2 production protein luxs | protein | 151 | 35% helix, 20% strand | Q9ZMW8 |
| B | Autoinducer-2 production protein luxs | protein | 152 | 36% helix, 20% strand | Q9ZMW8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.72 | 0.93 | 30 | MET |
| 2 | 144 | 0.70 | 0.90 | 33 | ZN, MET |
Interfaces
1 interface between chains.
- A–B · 2308 Ų buried · 45 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ZMW8
- Elsewhere: RCSB PDB 1J6X · PDBe 1J6X · UniProt Q9ZMW8
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