MolNFT v1 · #109034 · protein
Crystal structure of cytochrome P450 CYP107W1 from streptomyces avermitilis in complex with oligomycin a
4WQ0: “Crystal structure of cytochrome P450 CYP107W1 from streptomyces avermitilis in complex with oligomycin a”. X-ray diffraction, 2 ligands (HEM, EFO), 4 pockets (best druggability 0.83). MolNFT v1 #109034 on GenesisL1: 3D structure…
- PDB
- 4WQ0
- Type
- protein
- Length
- 397 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450
- UniProt
- Q93HJ0
- Ligands
- HEM, EFO
- Pockets
- 4 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 | protein | 397 | 52% helix, 9% strand | Q93HJ0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 913 | 0.83 | 0.85 | 84 | HEM, EFO |
| 2 | 162 | 0.61 | 0.84 | 30 | empty |
| 3 | 80 | 0.41 | 0.79 | 17 | empty |
| 4 | 99 | 0.38 | 0.75 | 22 | empty |
Compared structures
- 4WQ0 · Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis in complex… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93HJ0
- Elsewhere: RCSB PDB 4WQ0 · PDBe 4WQ0 · UniProt Q93HJ0
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