MolNFT v1 · #10900 · protein
Crystal structure of indole-3-glycerol phosphate synthase (TM0140) from thermotoga maritima at 3.0 a resolution
1J5T: “Crystal structure of indole-3-glycerol phosphate synthase (TM0140) from thermotoga maritima at 3.0 a…”. X-ray diffraction, 1 ligand (CL), 3 pockets (best druggability 0.70). MolNFT v1 #10900 on GenesisL1: 3D structure, binding sites…
- PDB
- 1J5T
- Type
- protein
- Length
- 233 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Indole-3-glycerol phosphate synthase
- EC
- 4.1.1.48
- UniProt
- Q56319
- Ligands
- CL
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Indole-3-glycerol phosphate synthase (EC 4.1.1.48) | protein | 233 | 39% helix, 17% strand | Q56319 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 381 | 0.70 | 0.82 | 44 | empty |
| 2 | 98 | 0.65 | 0.89 | 21 | empty |
| 3 | 137 | 0.44 | 0.76 | 23 | empty |
Compared structures
- 1J5T · Crystal structure of indole-3-glycerol phosphate synthase (TM0140) from Thermotoga… · the same entry in another collection · chain A against A, TM-score 1.00
- Q56319 · AlphaFold monomer V2.0 prediction for indole-3-glycerol phosphate synthase (Q56319) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56319
- Elsewhere: RCSB PDB 1J5T · PDBe 1J5T · UniProt Q56319
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