MolNFT v1 · #108986 · protein
The substrate-free duplicated taurocyamine kinase from schistosoma mansoni
4WO8: “The substrate-free duplicated taurocyamine kinase from schistosoma mansoni”. X-ray diffraction, 4 pockets (best druggability 0.61). MolNFT v1 #108986 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4WO8
- Type
- protein
- Length
- 706 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Taurocyamine kinase
- EC
- 2.7.3.4
- UniProt
- P16641
- Pockets
- 4 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Taurocyamine kinase (EC 2.7.3.4) | protein | 706 | 38% helix, 17% strand | P16641 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 555 | 0.61 | 0.74 | 55 | empty |
| 2 | 244 | 0.48 | 0.74 | 38 | empty |
| 3 | 101 | 0.41 | 0.77 | 19 | empty |
| 4 | 86 | 0.33 | 0.74 | 20 | empty |
Compared structures
- 4WO8 · The substrate-free duplicated taurocyamine kinase from Schistosoma mansoni · the same entry in another collection · chain A against A, TM-score 1.00
- P16641 · AlphaFold monomer V2.0 prediction for taurocyamine kinase (P16641) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16641
- Elsewhere: RCSB PDB 4WO8 · PDBe 4WO8 · UniProt P16641
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