MolNFT v1 · #108985 · protein
Crystal structure of prsa from bacillus subtilis
4WO7 · Foldase protein prsa: “Crystal structure of prsa from bacillus subtilis”. X-ray diffraction, 5 pockets (best druggability 0.47). MolNFT v1 #108985 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4WO7
- Type
- protein
- Length
- 513 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Foldase protein prsa
- EC
- 5.2.1.8
- UniProt
- P24327
- Pockets
- 5 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 57% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Foldase protein prsa (EC 5.2.1.8) | protein | 257 | 56% helix, 14% strand | P24327 |
| B | Foldase protein prsa (EC 5.2.1.8) | protein | 256 | 57% helix, 13% strand | P24327 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 160 | 0.47 | 0.76 | 24 | empty |
| 2 | 118 | 0.42 | 0.76 | 23 | empty |
| 3 | 73 | 0.33 | 0.75 | 14 | empty |
| 4 | 63 | 0.28 | 0.73 | 13 | empty |
| 5 | 62 | 0.26 | 0.72 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1953 Ų buried · 17 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24327
- Elsewhere: RCSB PDB 4WO7 · PDBe 4WO7 · UniProt P24327
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