MolNFT v1 · #108949 · protein
Crystal structure of designed cppr-polya protein
4WN4 · Pentatricopeptide repeat protein: “Crystal structure of designed cppr-polya protein”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #108949 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4WN4
- Type
- protein
- Length
- 420 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pentatricopeptide repeat protein
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pentatricopeptide repeat protein | protein | 210 | 75% helix, 0% strand | — |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 212 | 0.53 | 0.78 | 33 | empty |
| 2 | 75 | 0.38 | 0.78 | 15 | empty |
| 3 | 56 | 0.26 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 451 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 4WN4 · Crystal structure of designed cPPR-polyA protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4WN4 · PDBe 4WN4
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