MolNFT v1 · #108760 · protein
Human CEACAM6 N-domain
4WHC · Carcinoembryonic antigen-related cell adhesion molecule 6: “Human CEACAM6 N-domain”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.43). MolNFT v1 #108760 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4WHC
- Type
- protein
- Length
- 215 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carcinoembryonic antigen-related cell adhesion molecule 6
- UniProt
- P40199
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Carcinoembryonic antigen-related cell adhesion molecule 6 | protein | 107 | 6% helix, 51% strand | P40199 |
| B | Carcinoembryonic antigen-related cell adhesion molecule 6 | protein | 108 | 6% helix, 51% strand | P40199 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 84 | 0.43 | 0.79 | 24 | empty |
| 2 | 106 | 0.37 | 0.74 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 430 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40199
- Elsewhere: RCSB PDB 4WHC · PDBe 4WHC · UniProt P40199
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