MolNFT v1 · #108752 · protein

Protein GB1 quadruple mutant I6H/N8H/K28H/Q32H

4WH4 · Immunoglobulin G-binding protein G: “Protein GB1 quadruple mutant I6H/N8H/K28H/Q32H”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.49). MolNFT v1 #108752 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 4WH4
Type: protein
Length: 112 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Immunoglobulin G-binding protein G
UniProt: P19909
Ligands: SO4
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Immunoglobulin G-binding protein G	protein	56	30% helix, 43% strand	P19909

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A
GOL · Glycerol · additive · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.49	0.83	27	empty

Interfaces

1 interface between chains.

A–B · 456 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

4WH4 · Protein GB1 Quadruple Mutant I6H/N8H/K28H/Q32H · the same entry in another collection · chain A against A, TM-score 1.00
P19909 · AlphaFold monomer V2.0 prediction for immunoglobulin G-binding protein G (P19909) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19909
Elsewhere: RCSB PDB 4WH4 · PDBe 4WH4 · UniProt P19909

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.