MolNFT v1 · #10855 · protein
Recombinant mouse-muscle adenylosuccinate synthetase
1J4B: “Recombinant mouse-muscle adenylosuccinate synthetase”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #10855 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1J4B
- Type
- protein
- Length
- 432 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenylosuccinate synthetase
- EC
- 6.3.4.4
- UniProt
- P28650
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenylosuccinate synthetase (EC 6.3.4.4) | protein | 432 | 38% helix, 21% strand | P28650 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 922 | 0.75 | 0.79 | 90 | empty |
| 2 | 81 | 0.46 | 0.81 | 17 | empty |
| 3 | 55 | 0.32 | 0.77 | 12 | empty |
Compared structures
- 1J4B · Recombinant Mouse-Muscle Adenylosuccinate Synthetase · the same entry in another collection · chain A against A, TM-score 1.00
- P28650 · AlphaFold monomer V2.0 prediction for adenylosuccinate synthetase isozyme 1 (P28650) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28650
- Elsewhere: RCSB PDB 1J4B · PDBe 1J4B · UniProt P28650
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.