MolNFT v1 · #108406 · protein
The structure of vaccina virus H7 protein displays a novel phosphoinositide binding fold required for membrane biogenesis
4W5X · Late protein H7: “The structure of vaccina virus H7 protein displays a novel phosphoinositide binding fold required for…”. X-ray diffraction, 2 pockets (best druggability 0.31). MolNFT v1 #108406 on GenesisL1: 3D structure, binding…
- PDB
- 4W5X
- Type
- protein
- Length
- 233 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Late protein H7
- UniProt
- P08586
- Pockets
- 2 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Late protein H7 | protein | 116 | 54% helix, 13% strand | P08586 |
| A | Late protein H7 | protein | 117 | 55% helix, 13% strand | P08586 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.31 | 0.74 | 21 | empty |
| 2 | 70 | 0.30 | 0.73 | 11 | empty |
Interfaces
1 interface between chains.
- B–A · 200 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4W5X · The structure of Vaccina virus H7 protein displays A Novel Phosphoinositide binding fold… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08586
- Elsewhere: RCSB PDB 4W5X · PDBe 4W5X · UniProt P08586
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