MolNFT v1 · #108330 · protein
Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link
4V3N · Pleurotolysin a: “Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link”. Electron microscopy, 1 pocket (best druggability 0.41). MolNFT v1 #108330 on GenesisL1: 3D structure, binding…
- PDB
- 4V3N
- Type
- protein
- Length
- 658 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pleurotolysin a; Pleurotolysin B
- UniProt
- Q8X1M9, Q5W9E8
- Pockets
- 1 · best druggability 0.41
Structure
electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pleurotolysin a | protein | 135 | 0% helix, 0% strand | Q8X1M9 |
| C | Pleurotolysin B | protein | 388 | 0% helix, 0% strand | Q5W9E8 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.41 | 0.73 | 38 | empty |
Interfaces
1 interface between chains.
- A–B · 134 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4V3N · Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8X1M9
- Every structure of UniProt Q5W9E8
- Elsewhere: RCSB PDB 4V3N · PDBe 4V3N · UniProt Q8X1M9 · UniProt Q5W9E8
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