MolNFT v1 · #10832 · protein
Double mutant (C59R+S108N) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with pyrimethamine, NADPH, and dump
1J3J: “Double mutant (C59R+S108N) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts)…”. X-ray diffraction. MolNFT v1 #10832 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1J3J
- Type
- protein
- Length
- 1,089 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P13922
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 221 | — | P13922 |
| B | — | protein | 216 | — | P13922 |
| C, D | — | protein | 326 | — | P13922 |
Compared structures
- 1J3J · Double mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate… · the same entry in another collection · chain D against D, TM-score 1.00
- P13922 · AlphaFold monomer V2.0 prediction for bifunctional dihydrofolate reductase-thymidylate… · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13922
- Elsewhere: RCSB PDB 1J3J · PDBe 1J3J · UniProt P13922
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