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MolNFT v1 · #108144 · protein

Cytoplasmic domain of bacterial cell division protein ezra

4UXV · Septation ring formation regulator ezra: “Cytoplasmic domain of bacterial cell division protein ezra”. X-ray diffraction, 7 pockets (best druggability 0.67). MolNFT v1 #108144 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
4UXV
Type
protein
Length
522 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Septation ring formation regulator ezra
UniProt
O34894
Pockets
7 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASeptation ring formation regulator ezraprotein52268% helix, 0% strandO34894

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11840.670.8624empty
21560.580.8226empty
31050.570.8526empty
4750.560.8614empty
5630.490.8419empty

Compared structures

  • 4UXV · Cytoplasmic domain of bacterial cell division protein EzrA · the same entry in another collection · chain A against A, TM-score 1.00
  • O34894 · AlphaFold monomer V2.0 prediction for septation ring formation regulator ezra (O34894) · a predicted model of the same protein · chain A against A, TM-score 0.73

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