MolNFT v1 · #108050 · protein
Structure of the curli transport lipoprotein csgg in its membrane-bound conformation
4UV3 · Curli production ASSEMBLY/TRANSPORT component csgg: “Structure of the curli transport lipoprotein csgg in its membrane-bound conformation”. X-ray diffraction, 20 pockets (best druggability 0.82). MolNFT v1 #108050 on GenesisL1: 3D…
- PDB
- 4UV3
- Type
- protein
- Length
- 4,451 residues
- Chains
- 18
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Curli production ASSEMBLY/TRANSPORT component csgg
- UniProt
- P0AEA2
- Pockets
- 20 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D, H, J | Curli production ASSEMBLY/TRANSPORT component csgg | protein | 248 | 28% helix, 37% strand | P0AEA2 |
| C, E, F, G, I, K, L, M, N, O, P, Q, R | Curli production ASSEMBLY/TRANSPORT component csgg | protein | 247 | 28% helix, 36% strand | P0AEA2 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1173 | 0.82 | 0.83 | 182 | empty |
| 2 | 783 | 0.67 | 0.75 | 64 | empty |
| 3 | 787 | 0.66 | 0.74 | 65 | empty |
| 4 | 185 | 0.65 | 0.85 | 39 | empty |
| 5 | 166 | 0.64 | 0.85 | 36 | empty |
Interfaces
45 interfaces between chains.
- O–P · 3092 Ų buried · 60 hydrogen bonds · protein-protein
- F–G · 3078 Ų buried · 67 hydrogen bonds · protein-protein
- H–I · 3069 Ų buried · 64 hydrogen bonds · protein-protein
- N–O · 3063 Ų buried · 66 hydrogen bonds · protein-protein
- G–H · 3056 Ų buried · 63 hydrogen bonds · protein-protein
Compared structures
- 4UV3 · Structure of the curli transport lipoprotein CsgG in its membrane- bound conformation · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEA2
- Elsewhere: RCSB PDB 4UV3 · PDBe 4UV3 · UniProt P0AEA2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.