MolNFT v1 · #107831 · protein

Crystal structure of deinococcus radiodurans endonuclease III-3

4UOB: “Crystal structure of deinococcus radiodurans endonuclease III-3”. X-ray diffraction, 3 ligands (SF4, CO, SO4), 2 pockets (best druggability 0.58). MolNFT v1 #107831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4UOB
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endonuclease III-3
EC: 4.2.99.18
UniProt: Q9RVU4
Ligands: SF4, CO, SO4
Pockets: 2 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endonuclease III-3 (EC 4.2.99.18)	protein	242	64% helix, 0% strand	Q9RVU4

Ligands and binding sites

SF4 · Iron/sulfur cluster · ligand · chains A
CO · Cobalt (II) ion · metal · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A
ACT · Acetate ion · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	335	0.58	0.76	29	SO4
2	116	0.43	0.77	19	empty

Compared structures

4UOB · Crystal structure of Deinococcus radiodurans Endonuclease III-3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9RVU4
Elsewhere: RCSB PDB 4UOB · PDBe 4UOB · UniProt Q9RVU4

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