MolNFT v1 · #107505 · protein

N-terminal globular domain of the rsv nucleoprotein in complex with C-terminal peptide of the phosphoprotein

4UCA: “N-terminal globular domain of the rsv nucleoprotein in complex with C-terminal peptide of the phosphoprotein”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.55). MolNFT v1 #107505 on GenesisL1: 3D structure…

PDB: 4UCA
Type: protein
Length: 440 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoprotein; Phosphosprotein
UniProt: P03418
Ligands: SO4
Pockets: 5 · best druggability 0.55

Structure

x-ray diffraction · 3 distinct chains · 62% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoprotein	protein	219	62% helix, 9% strand	P03418
B	Nucleoprotein	protein	220	62% helix, 8% strand	P03418
C	Phosphosprotein	protein	1	0% helix, 0% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	310	0.55	0.76	32	SO4
2	256	0.55	0.77	27	empty
3	103	0.53	0.83	19	empty
4	87	0.37	0.76	17	empty
5	53	0.31	0.76	11	empty

Interfaces

2 interfaces between chains.

A–B · 481 Å² buried · 8 hydrogen bonds · protein-protein
A–C · 199 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

4UCA · N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03418
Elsewhere: RCSB PDB 4UCA · PDBe 4UCA · UniProt P03418

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