MolNFT v1 · #107495 · protein
Crystal structure of a purine nucleoside phosphorylase (psi-nysgrc- 029736) from agrobacterium vitis
4UC0: “Crystal structure of a purine nucleoside phosphorylase (psi-nysgrc- 029736) from agrobacterium vitis”. X-ray diffraction, 1 ligand (HPA), 1 pocket (best druggability 0.42). MolNFT v1 #107495 on GenesisL1: 3D structure, binding sites…
- PDB
- 4UC0
- Type
- protein
- Length
- 247 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Purine nucleoside phosphorylase
- EC
- 2.4.2.1
- UniProt
- B9JYS2
- Ligands
- HPA
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Purine nucleoside phosphorylase (EC 2.4.2.1) | protein | 247 | 33% helix, 27% strand | B9JYS2 |
Ligands and binding sites
- HPA · Hypoxanthine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.42 | 0.77 | 25 | HPA |
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 4UC0 · Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B9JYS2
- Elsewhere: RCSB PDB 4UC0 · PDBe 4UC0 · UniProt B9JYS2
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