MolNFT v1 · #107264 · protein
Crystal structure of salmonella alpha-2-macroglobulin reacted with methylamine
4U59: “Crystal structure of salmonella alpha-2-macroglobulin reacted with methylamine”. X-ray diffraction, 15 pockets (best druggability 0.79). MolNFT v1 #107264 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4U59
- Type
- protein
- Length
- 1,538 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-2-macroglobulin
- UniProt
- Q8ZN46
- Pockets
- 15 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-2-macroglobulin | protein | 1538 | 14% helix, 40% strand | Q8ZN46 |
Pockets
15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 811 | 0.79 | 0.83 | 63 | empty |
| 2 | 1092 | 0.76 | 0.78 | 91 | empty |
| 3 | 934 | 0.75 | 0.78 | 94 | empty |
| 4 | 103 | 0.70 | 0.92 | 24 | empty |
| 5 | 369 | 0.65 | 0.79 | 44 | empty |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 4U59 · Crystal structure of Salmonella alpha-2-macroglobulin reacted with methylamine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZN46
- Elsewhere: RCSB PDB 4U59 · PDBe 4U59 · UniProt Q8ZN46
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