MolNFT v1 · #107258 · protein
Structure of a NITRATE/NITRITE antiporter nark in nitrate-bound inward-open state
4U4T · NITRATE/NITRITE transporter nark: “Structure of a NITRATE/NITRITE antiporter nark in nitrate-bound inward-open state”. X-ray diffraction, 3 ligands (OLA, ZN, NO3), 2 pockets (best druggability 0.65). MolNFT v1 #107258 on GenesisL1…
- PDB
- 4U4T
- Type
- protein
- Length
- 444 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NITRATE/NITRITE transporter nark
- UniProt
- P10903
- Ligands
- OLA, ZN, NO3
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 80% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NITRATE/NITRITE transporter nark | protein | 444 | 80% helix, 1% strand | P10903 |
Ligands and binding sites
- OLA · Oleic acid · ligand · 2 copies · chains A
- ZN · Zinc ion · metal · chains A
- NO3 · Nitrate ion · ion · chains A
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 510 | 0.65 | 0.77 | 51 | empty |
| 2 | 113 | 0.44 | 0.78 | 21 | empty |
Compared structures
- 4U4T · Structure of a nitrate/nitrite antiporter NarK in nitrate-bound inward-open state · the same entry in another collection · chain A against A, TM-score 1.00
- P10903 · AlphaFold monomer V2.0 prediction for NITRATE/NITRITE transporter nark (P10903) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10903
- Elsewhere: RCSB PDB 4U4T · PDBe 4U4T · UniProt P10903
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