MolNFT v1 · #107232 · protein
Structure of a human vh antibody domain binding to the cleft of hen egg lysozyme
4U3X · Human vh domain antibody: “Structure of a human vh antibody domain binding to the cleft of hen egg lysozyme”. X-ray diffraction. MolNFT v1 #107232 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4U3X
- Type
- protein
- Length
- 486 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Human vh domain antibody; Lysozyme C
- EC
- 3.2.1.17
- UniProt
- P00698
Structure
x-ray diffraction · 3 distinct chains · 20% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Human vh domain antibody | protein | 119 | 10% helix, 50% strand | — |
| B, D | Lysozyme C (EC 3.2.1.17) | protein | 128 | 41% helix, 11% strand | P00698 |
| C | Human vh domain antibody | protein | 111 | 5% helix, 49% strand | — |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
2 interfaces between chains.
- A–B · 835 Ų buried · 21 hydrogen bonds · protein-protein
- C–D · 821 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 disulfide (disulfide).
Compared structures
- 4U3X · Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00698
- Elsewhere: RCSB PDB 4U3X · PDBe 4U3X · UniProt P00698
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