MolNFT v1 · #107214 · protein
Crystal structure of CTCEL5E
4U3A · Endoglucanase H: “Crystal structure of CTCEL5E”. X-ray diffraction, 7 pockets (best druggability 0.55). MolNFT v1 #107214 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4U3A
- Type
- protein
- Length
- 586 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoglucanase H
- EC
- 3.2.1.4
- UniProt
- P16218
- Pockets
- 7 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoglucanase H (EC 3.2.1.4) | protein | 292 | 42% helix, 18% strand | P16218 |
| B | Endoglucanase H (EC 3.2.1.4) | protein | 294 | 41% helix, 17% strand | P16218 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 284 | 0.55 | 0.76 | 29 | empty |
| 2 | 156 | 0.50 | 0.78 | 22 | empty |
| 3 | 50 | 0.43 | 0.83 | 20 | empty |
| 4 | 79 | 0.38 | 0.78 | 20 | empty |
| 5 | 76 | 0.34 | 0.76 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 379 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16218
- Elsewhere: RCSB PDB 4U3A · PDBe 4U3A · UniProt P16218
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