MolNFT v1 · #107085 · protein

Structure of metallo-beta lactamase

4TZF · Ndm-8 metallo-beta-lactamase: “Structure of metallo-beta lactamase”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.42). MolNFT v1 #107085 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4TZF
Type: protein
Length: 229 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ndm-8 metallo-beta-lactamase
UniProt: M1VE66
Ligands: ZN
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ndm-8 metallo-beta-lactamase	protein	229	27% helix, 31% strand	M1VE66

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	126	0.42	0.75	19	empty

Compared structures

4TZF · Structure of metallo-beta lactamase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt M1VE66
Elsewhere: RCSB PDB 4TZF · PDBe 4TZF · UniProt M1VE66

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