MolNFT v1 · #107077 · protein
Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from zebrafish
4TZ7 · Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha: “Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from zebrafish”. X-ray diffraction, 3 pockets (best druggability 0.68). MolNFT v1 #107077 on…
- PDB
- 4TZ7
- Type
- protein
- Length
- 303 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
- UniProt
- Q503I3
- Pockets
- 3 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | protein | 303 | 35% helix, 23% strand | Q503I3 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 707 | 0.68 | 0.76 | 75 | empty |
| 2 | 62 | 0.40 | 0.81 | 20 | empty |
| 3 | 58 | 0.34 | 0.77 | 14 | empty |
Compared structures
- 4TZ7 · Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q503I3
- Elsewhere: RCSB PDB 4TZ7 · PDBe 4TZ7 · UniProt Q503I3
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