MolNFT v1 · #107011 · protein
Crystal structure of the X-domain from teicoplanin biosynthesis
4TX2 · Non-ribosomal peptide synthetase: “Crystal structure of the X-domain from teicoplanin biosynthesis”. X-ray diffraction, 5 pockets (best druggability 0.79). MolNFT v1 #107011 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4TX2
- Type
- protein
- Length
- 452 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-ribosomal peptide synthetase
- UniProt
- Q70AZ6
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Non-ribosomal peptide synthetase | protein | 452 | 35% helix, 20% strand | Q70AZ6 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1065 | 0.79 | 0.81 | 90 | empty |
| 2 | 56 | 0.67 | 0.96 | 21 | empty |
| 3 | 66 | 0.51 | 0.85 | 16 | empty |
| 4 | 219 | 0.49 | 0.75 | 33 | empty |
| 5 | 106 | 0.42 | 0.77 | 20 | empty |
Compared structures
- 4TX2 · Crystal structure of the X-domain from teicoplanin biosynthesis · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q70AZ6
- Elsewhere: RCSB PDB 4TX2 · PDBe 4TX2 · UniProt Q70AZ6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.