MolNFT v1 · #106853 · protein

Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) from zebrafish

4TS4: “Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) from…”. X-ray diffraction, 2 pockets (best druggability 0.63). MolNFT v1 #106853 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 4TS4
Type: protein
Length: 308 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 10-formyltetrahydrofolate dehydrogenase
EC: 1.5.1.6
UniProt: E3NZ06
Pockets: 2 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6)	protein	308	27% helix, 27% strand	E3NZ06

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	387	0.63	0.77	43	empty
2	63	0.28	0.73	18	empty

Compared structures

4TS4 · Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E3NZ06
Elsewhere: RCSB PDB 4TS4 · PDBe 4TS4 · UniProt E3NZ06

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