MolNFT v1 · #106845 · protein

Structure of BACE1 complex with a syn-hea-type inhibitor

4TRW: “Structure of BACE1 complex with a syn-hea-type inhibitor”. X-ray diffraction. MolNFT v1 #106845 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4TRW
Type: protein
Length: 1,177 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P56817

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	389	—	P56817
C	—	protein	390	—	P56817
D, E, F	—	protein	3	—	—

Compared structures

4TRW · Structure of BACE1 complex with a syn-HEA-type inhibitor · the same entry in another collection · chain F against F, TM-score 1.00
P56817 · AlphaFold monomer V2.0 prediction for beta-secretase 1 (P56817) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56817
Elsewhere: RCSB PDB 4TRW · PDBe 4TRW · UniProt P56817

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