MolNFT v1 · #10684 · protein
Lipoyl domain of pyruvate dehydrogenase complex, NMR, 29 structures
1IYV · Dihydrolipoamide acetyltransferase component of pyruvate…: “Lipoyl domain of pyruvate dehydrogenase complex, NMR, 29 structures”. Solution nmr, 1 pocket (best druggability 0.58). MolNFT v1 #10684 on GenesisL1: 3D structure, binding…
- PDB
- 1IYV
- Type
- protein
- Length
- 79 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- EC
- 2.3.1.12
- UniProt
- P10802
- Pockets
- 1 · best druggability 0.58
Structure
solution nmr · 1 distinct chain · 0% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) | protein | 79 | 0% helix, 43% strand | P10802 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.58 | 0.87 | 29 | empty |
Compared structures
- 1IYV · Lipoyl domain of pyruvate dehydrogenase complex, NMR, 29 structures · the same entry in another collection · chain A against A, TM-score 1.00
- P10802 · AlphaFold monomer V2.0 prediction for dihydrolipoyllysine-residue acetyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10802
- Elsewhere: RCSB PDB 1IYV · PDBe 1IYV · UniProt P10802
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