MolNFT v1 · #106703 · protein
Crystal structure of the C-terminal periplasmic domain of phosphoethanolamine transferase eptc from campylobacter jejuni
4TN0 · UPF0141 protein yjdb: “Crystal structure of the C-terminal periplasmic domain of phosphoethanolamine transferase eptc from…”. X-ray diffraction, 1 ligand (ZN), 7 pockets (best druggability 0.46). MolNFT v1 #106703 on GenesisL1: 3D…
- PDB
- 4TN0
- Type
- protein
- Length
- 923 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UPF0141 protein yjdb
- UniProt
- A3ZEY5
- Ligands
- ZN
- Pockets
- 7 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 34% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | UPF0141 protein yjdb | protein | 308 | 34% helix, 18% strand | A3ZEY5 |
| B | UPF0141 protein yjdb | protein | 307 | 34% helix, 18% strand | A3ZEY5 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.46 | 0.83 | 16 | empty |
| 2 | 72 | 0.45 | 0.82 | 16 | empty |
| 3 | 63 | 0.40 | 0.80 | 17 | empty |
| 4 | 58 | 0.33 | 0.77 | 15 | empty |
| 5 | 58 | 0.31 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- B–C · 35 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 disulfide, 3 modified (disulfide, phosphorylation).
Compared structures
- 4TN0 · Crystal Structure of the C-terminal Periplasmic Domain of Phosphoethanolamine Transferase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3ZEY5
- Elsewhere: RCSB PDB 4TN0 · PDBe 4TN0 · UniProt A3ZEY5
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