MolNFT v1 · #106667 · protein

Crystal structure of C-terminal RNA recognition motif of human elav type RNA binding protein-3 at 2.5 ångström resolution

4TLQ · Cugbp elav-like family member 2: “Crystal structure of C-terminal RNA recognition motif of human elav type RNA binding protein-3 at 2.5…”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #106667 on GenesisL1: 3D…

PDB: 4TLQ
Type: protein
Length: 165 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cugbp elav-like family member 2
UniProt: O95319
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cugbp elav-like family member 2	protein	82	27% helix, 37% strand	O95319
B	Cugbp elav-like family member 2	protein	83	27% helix, 36% strand	O95319

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.41	0.78	17	empty

Interfaces

1 interface between chains.

A–B · 431 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

4TLQ · Crystal structure of C-terminal RNA recognition motif of human ELAV type RNA binding… · the same entry in another collection · chain A against A, TM-score 1.00
O95319 · AlphaFold monomer V2.0 prediction for cugbp elav-like family member 2 (O95319) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95319
Elsewhere: RCSB PDB 4TLQ · PDBe 4TLQ · UniProt O95319

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