MolNFT v1 · #106452 · protein
Crystal structure of fabg from synechocystis sp. pcc 6803
4RZH · 3-oxoacyl-[acyl-carrier protein] reductase: “Crystal structure of fabg from synechocystis sp. pcc 6803”. X-ray diffraction, 4 pockets (best druggability 0.57). MolNFT v1 #106452 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4RZH
- Type
- protein
- Length
- 468 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-oxoacyl-[acyl-carrier protein] reductase
- UniProt
- M1M4P9
- Pockets
- 4 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 3-oxoacyl-[acyl-carrier protein] reductase | protein | 234 | 53% helix, 17% strand | M1M4P9 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 340 | 0.57 | 0.76 | 45 | empty |
| 2 | 277 | 0.55 | 0.76 | 40 | empty |
| 3 | 82 | 0.46 | 0.81 | 17 | empty |
| 4 | 50 | 0.25 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1467 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 4RZH · Crystal structure of FabG from Synechocystis sp. PCC 6803 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt M1M4P9
- Elsewhere: RCSB PDB 4RZH · PDBe 4RZH · UniProt M1M4P9
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