MolNFT v1 · #106323 · protein

The native structure of mycobacterial quinone oxidoreductase RV154C.

4RVS · Probable quinone reductase qor (NADPH:QUINONE reductase)…: “The native structure of mycobacterial quinone oxidoreductase RV154C.”. X-ray diffraction, 4 pockets (best druggability 0.69). MolNFT v1 #106323 on GenesisL1: 3D structure…

PDB: 4RVS
Type: protein
Length: 658 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable quinone reductase qor (NADPH:QUINONE reductase) (zeta-crystallin homolog protein)
UniProt: O53146
Pockets: 4 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Probable quinone reductase qor (NADPH:QUINONE reductase) (zeta-crystallin homolog protein)	protein	329	33% helix, 28% strand	O53146

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	728	0.69	0.76	66	empty
2	773	0.69	0.76	70	empty
3	126	0.37	0.73	23	empty
4	66	0.30	0.74	20	empty

Interfaces

1 interface between chains.

A–B · 1231 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

4RVS · The native structure of mycobacterial qui oxidoreductase Rv154c. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O53146
Elsewhere: RCSB PDB 4RVS · PDBe 4RVS · UniProt O53146

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