MolNFT v1 · #10631 · protein

Crystal structure of cbnr, a lysr family transcriptional regulator

1IXC · Lysr-type regulatory protein: “Crystal structure of cbnr, a lysr family transcriptional regulator”. X-ray diffraction, 6 pockets (best druggability 0.53). MolNFT v1 #10631 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1IXC
Type: protein
Length: 578 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysr-type regulatory protein
UniProt: Q9WXC7
Pockets: 6 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysr-type regulatory protein	protein	289	48% helix, 23% strand	Q9WXC7
B	Lysr-type regulatory protein	protein	289	45% helix, 25% strand	Q9WXC7

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.53	0.84	22	empty
2	66	0.52	0.86	20	empty
3	84	0.40	0.78	20	empty
4	61	0.31	0.76	13	empty
5	62	0.30	0.74	13	empty

Interfaces

1 interface between chains.

A–B · 1124 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

1IXC · Crystal structure of CbnR, a LysR family transcriptional regulator · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9WXC7
Elsewhere: RCSB PDB 1IXC · PDBe 1IXC · UniProt Q9WXC7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.