MolNFT v1 · #106049 · protein
Pamora phosphodiesterase domain, apo form
4RNJ · Motility regulator: “Pamora phosphodiesterase domain, apo form”. X-ray diffraction, 5 pockets (best druggability 0.69). MolNFT v1 #106049 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4RNJ
- Type
- protein
- Length
- 509 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Motility regulator
- EC
- 3.1.4.52
- UniProt
- Q9HVI8
- Pockets
- 5 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Motility regulator (EC 3.1.4.52) | protein | 255 | 49% helix, 21% strand | Q9HVI8 |
| B | Motility regulator (EC 3.1.4.52) | protein | 254 | 51% helix, 20% strand | Q9HVI8 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.69 | 0.95 | 17 | empty |
| 2 | 529 | 0.66 | 0.77 | 51 | empty |
| 3 | 303 | 0.58 | 0.77 | 35 | empty |
| 4 | 76 | 0.51 | 0.84 | 13 | empty |
| 5 | 69 | 0.37 | 0.78 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 803 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 4RNJ · PaMorA phosphodiesterase domain, apo form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HVI8
- Elsewhere: RCSB PDB 4RNJ · PDBe 4RNJ · UniProt Q9HVI8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.