MolNFT v1 · #105965 · protein

Structural and functional analysis of a loading acyltransferase from the avermectin modular polyketide synthase

4RL1 · Type I polyketide synthase aves 1: “Structural and functional analysis of a loading acyltransferase from the avermectin modular polyketide…”. X-ray diffraction, 1 pocket (best druggability 0.68). MolNFT v1 #105965 on GenesisL1: 3D…

PDB: 4RL1
Type: protein
Length: 318 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type I polyketide synthase aves 1
EC: 2.3.1.39
UniProt: Q79ZN1
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Type I polyketide synthase aves 1 (EC 2.3.1.39)	protein	318	49% helix, 15% strand	Q79ZN1

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	234	0.68	0.85	40	empty

Compared structures

4RL1 · Structural and functional analysis of a loading acyltransferase from the avermectin… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q79ZN1
Elsewhere: RCSB PDB 4RL1 · PDBe 4RL1 · UniProt Q79ZN1

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