MolNFT v1 · #105861 · protein
Crystal structure of a hypothetical protein (BPSL2088) from burkholderia pseudomallei K96243 at 2.25 a resolution
4RHO · Uncharacterized protein: “Crystal structure of a hypothetical protein (BPSL2088) from burkholderia pseudomallei K96243 at 2.25 a…”. X-ray diffraction, 5 pockets (best druggability 0.84). MolNFT v1 #105861 on GenesisL1: 3D structure…
- PDB
- 4RHO
- Type
- protein
- Length
- 513 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q63T80
- Pockets
- 5 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 256 | 28% helix, 22% strand | Q63T80 |
| B | Uncharacterized protein | protein | 257 | 28% helix, 22% strand | Q63T80 |
Ligands and binding sites
- PGE · Triethylene glycol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 833 | 0.84 | 0.86 | 98 | empty |
| 2 | 240 | 0.66 | 0.83 | 21 | PGE |
| 3 | 245 | 0.64 | 0.82 | 20 | PGE |
| 4 | 197 | 0.53 | 0.78 | 34 | empty |
| 5 | 75 | 0.39 | 0.78 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 919 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 4RHO · Crystal structure of a hypothetical protein (BPSL2088) from Burkholderia pseudomallei… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q63T80
- Elsewhere: RCSB PDB 4RHO · PDBe 4RHO · UniProt Q63T80
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.