MolNFT v1 · #105815 · RNA
Crystal structure of the in-line aligned ENV22 twister ribozyme
4RGE: “Crystal structure of the in-line aligned ENV22 twister ribozyme”. X-ray diffraction, 1 ligand (MG), 10 pockets (best druggability 0.69). MolNFT v1 #105815 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4RGE
- Type
- RNA
- Length
- 167 nucleotides
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ENV22 twister ribozyme
- Ligands
- MG
- Pockets
- 10 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ENV22 twister ribozyme | rna | 56 | — | — |
| C | ENV22 twister ribozyme | rna | 55 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 27 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.69 | 0.80 | 37 | MG |
| 2 | 269 | 0.61 | 0.81 | 27 | MG |
| 3 | 179 | 0.60 | 0.83 | 16 | MG |
| 4 | 403 | 0.59 | 0.76 | 28 | MG |
| 5 | 180 | 0.52 | 0.79 | 15 | MG |
Interfaces
1 interface between chains.
- B–C · 294 Ų buried · 6 hydrogen bonds · nucleic-nucleic
Compared structures
- 4RGE · Crystal structure of the in-line aligned env22 twister ribozyme · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4RGE · PDBe 4RGE
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.