MolNFT v1 · #105346 · protein
Crystal structure of beta-glycosidase BGL167
4R27 · Glycoside hydrolase: “Crystal structure of beta-glycosidase BGL167”. X-ray diffraction, 7 pockets (best druggability 0.82). MolNFT v1 #105346 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4R27
- Type
- protein
- Length
- 824 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycoside hydrolase
- EC
- 3.2.1.-
- UniProt
- L0ELG0
- Pockets
- 7 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycoside hydrolase (EC 3.2.1.-) | protein | 417 | 45% helix, 17% strand | L0ELG0 |
| B | Glycoside hydrolase (EC 3.2.1.-) | protein | 407 | 45% helix, 17% strand | L0ELG0 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.82 | 0.97 | 30 | empty |
| 2 | 554 | 0.80 | 0.86 | 65 | empty |
| 3 | 522 | 0.80 | 0.86 | 51 | empty |
| 4 | 363 | 0.74 | 0.85 | 34 | empty |
| 5 | 98 | 0.42 | 0.77 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 936 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4R27 · Crystal structure of beta-glycosidase BGL167 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L0ELG0
- Elsewhere: RCSB PDB 4R27 · PDBe 4R27 · UniProt L0ELG0
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