MolNFT v1 · #105343 · protein + DNA
Complete dissection of B. subtilis nitrogen homeostatic circuitry
4R24 · Hth-type transcriptional regulator tnra: “Complete dissection of B. subtilis nitrogen homeostatic circuitry”. X-ray diffraction, 1 pocket (best druggability 0.28). MolNFT v1 #105343 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4R24
- Type
- protein + DNA
- Length
- 106 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hth-type transcriptional regulator tnra; DNA (5'…
- UniProt
- G2RUZ1
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains · 64% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Hth-type transcriptional regulator tnra | protein | 85 | 64% helix, 7% strand | G2RUZ1 |
| G | DNA (5'- D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)- 3') | dna | 21 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.28 | 0.74 | 10 | empty |
Interfaces
1 interface between chains.
- B–G · 346 Ų buried · 11 hydrogen bonds · protein-nucleic
Compared structures
- 4R24 · Complete dissection of B. subtilis nitrogen homeostatic circuitry · the same entry in another collection · chain B against B, TM-score 1.00
- G2RUZ1 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator tnra (G2RUZ1) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G2RUZ1
- Elsewhere: RCSB PDB 4R24 · PDBe 4R24 · UniProt G2RUZ1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.