MolNFT v1 · #105341 · protein + DNA
Tnra-DNA complex
4R22 · Hth-type transcriptional regulator tnra: “Tnra-DNA complex”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #105341 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4R22
- Type
- protein + DNA
- Length
- 103 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hth-type transcriptional regulator tnra; DNA (5'…
- UniProt
- G2RUZ1
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Hth-type transcriptional regulator tnra | protein | 82 | 61% helix, 11% strand | G2RUZ1 |
| G | DNA (5'- D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)- 3') | dna | 21 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.33 | 0.74 | 11 | empty |
Interfaces
1 interface between chains.
- B–G · 349 Ų buried · 11 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G2RUZ1
- Elsewhere: RCSB PDB 4R22 · PDBe 4R22 · UniProt G2RUZ1
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