MolNFT v1 · #105323 · protein

Structure and function of neisseria gonorrhoeae mtrf illuminates a class of antimetabolite efflux pumps

4R1I · Aminobenzoyl-glutamate transporter: “Structure and function of neisseria gonorrhoeae mtrf illuminates a class of antimetabolite efflux pumps”. X-ray diffraction, 20 pockets (best druggability 0.74). MolNFT v1 #105323 on GenesisL1…

PDB: 4R1I
Type: protein
Length: 1,013 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aminobenzoyl-glutamate transporter
UniProt: D1DA20
Pockets: 20 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 58% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aminobenzoyl-glutamate transporter	protein	507	59% helix, 0% strand	D1DA20
B	Aminobenzoyl-glutamate transporter	protein	506	58% helix, 0% strand	D1DA20

Pockets

20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	707	0.74	0.79	51	empty
2	730	0.72	0.78	53	empty
3	508	0.67	0.77	51	empty
4	510	0.67	0.77	49	empty
5	213	0.61	0.81	26	empty

Interfaces

1 interface between chains.

A–B · 1811 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

4R1I · Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D1DA20
Elsewhere: RCSB PDB 4R1I · PDBe 4R1I · UniProt D1DA20

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