MolNFT v1 · #105322 · protein

Gntr family transcriptional regulator from listeria monocytogenes

4R1H · LMO0741 protein: “Gntr family transcriptional regulator from listeria monocytogenes”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #105322 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4R1H
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LMO0741 protein
UniProt: Q8Y901
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 2 distinct chains · 61% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LMO0741 protein	protein	116	60% helix, 8% strand	Q8Y901
B	LMO0741 protein	protein	114	61% helix, 8% strand	Q8Y901

Ligands and binding sites

ACT · Acetate ion · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.29	0.74	10	empty

Interfaces

1 interface between chains.

A–B · 1405 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

4R1H · GntR family transcriptional regulator from Listeria monocytogenes · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8Y901
Elsewhere: RCSB PDB 4R1H · PDBe 4R1H · UniProt Q8Y901

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.