MolNFT v1 · #105173 · protein
Crystal structure of the DNA-binding domain of the response regulator saer from staphylococcus aureus
4QWQ: “Crystal structure of the DNA-binding domain of the response regulator saer from staphylococcus aureus”. X-ray diffraction, 2 pockets (best druggability 0.32). MolNFT v1 #105173 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4QWQ
- Type
- protein
- Length
- 196 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Response regulator saer
- UniProt
- H9BRQ0
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 34% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Response regulator saer | protein | 100 | 34% helix, 28% strand | H9BRQ0 |
| A | Response regulator saer | protein | 96 | 34% helix, 28% strand | H9BRQ0 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.32 | 0.73 | 16 | empty |
| 2 | 53 | 0.25 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- B–A · 294 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4QWQ · Crystal structure of the DNA-binding domain of the response regulator SaeR from… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H9BRQ0
- Elsewhere: RCSB PDB 4QWQ · PDBe 4QWQ · UniProt H9BRQ0
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