Crystal structure of ANKRA2-RFX7 complex

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 0% strand (DSSP).

Ligands and binding sites

• UNL · Unknown ligand · ligand · chains A
• UNX · Unknown atom or ion · ion · 11 copies · chains A, X
• SO4 · Sulfate ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–X · 894 Ų buried · 9 hydrogen bonds · protein-protein

Compared structures

• 4QQI · Crystal structure of ANKRA2-RFX7 complex · the same entry in another collection · chain A against A, TM-score 1.00
• Q9H9E1 · AlphaFold monomer V2.0 prediction for ankyrin repeat family a protein 2 (Q9H9E1) · a predicted model of the same protein · chain A against A, TM-score 0.95
• Q2KHR2 · AlphaFold monomer V2.0 prediction for DNA-binding protein RFX7 (Q2KHR2) · a predicted model of the same protein · chain X against A, TM-score 0.35

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9H9E1
• Every structure of UniProt Q2KHR2
• Elsewhere: RCSB PDB 4QQI · PDBe 4QQI · UniProt Q9H9E1 · UniProt Q2KHR2